Use of Non-Steroidal Anti-Inflammatory Drugs That Elevate Cardiovascular Risk: An Examination of Sales and Essential Medicines Lists in Low-, Middle-, and High-Income Countries

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Demonstration of Single-Barium-Ion Sensitivity for Neutrinoless Double-Beta Decay Using Single-Molecule Fluorescence Imaging

[EN] A new method to tag the barium daughter in the double-beta decay of Xe-136 is reported. Using the technique of single molecule fluorescent imaging (SMFI), individual barium dication (Ba++) resolution at a transparent scanning surface is demonstrated. A single-step photobleach confirms the single ion interpretation. Individual ions are localized with superresolution (similar to 2 nm), and detected with a statistical significance of 12.9 sigma over backgrounds. This lays the foundation for a new and potentially background-free neutrinoless double-beta decay technology, based on SMFI coupled to high pressure xenon gas time projection chambers.NEXT Collaboration acknowledges support from the following agencies and institutions: the European Research Council (ERC) under Advanced Grant No. 339787-NEXT, the Ministerio de Economia y Competitividad of Spain under Grants No. FIS2014-53371-C04 and the Severo Ochoa Program SEV-2014-0398, the Generalitat Valenciana (GVA) of Spain under Grant No. PROMETEO/2016/120, the Portuguese FCT and FEDER through the program COMPETE, project PTDC/FIS/103860/2008, the U.S. Department of Energy under Contracts No. DE-AC02-07CH11359 (Fermi National Accelerator Laboratory) and No. DE-FG02-13ER42020 (Texas A&M) and No. DE-SC0017721 (University of Texas at Arlington), and the University of Texas at Arlington.Mcdonald, A.; Jones, B.; Nygren, D.; Adams, C.; Álvarez-Puerta, V.; Azevedo, C.; Benlloch-Rodríguez, J.... (2018). 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Galactic Gamma-Ray Diffuse Emission at TeV energies with HAWC Data

The Galactic gamma-ray diffuse emission (GDE) is emitted by cosmic rays (CRs), ultra-relativistic protons and electrons, interacting with gas and electromagnetic radiation fields in the interstellar medium. Here we present the analysis of TeV diffuse emission from a region of the Galactic Plane over the range in longitude of $l\in[43^\circ,73^\circ]$, using data collected with the High Altitude Water Cherenkov (HAWC) detector. Spectral, longitudinal and latitudinal distributions of the TeV diffuse emission are shown. The radiation spectrum is compatible with the spectrum of the emission arising from a CR population with an "index" similar to that of the observed CRs. When comparing with the \texttt{DRAGON} \textit{base model}, the HAWC GDE flux is higher by about a factor of two. Unresolved sources such as pulsar wind nebulae and TeV halos could explain the excess emission. Finally, deviations of the Galactic CR flux from the locally measured CR flux may additionally explain the difference between the predicted and measured diffuse fluxes